Even during the ongoing pandemic, infectious diseases remain largely ignored with respect to the discovery of innovative therapeutics and significant financial investments. Relevant communities prefer to stick to established approaches such as directly acting antivirals in response to upcoming threats. We at ATRIVA see a unique opportunity with a host cell-based anti-viral approach ultimately providing medicines for a world free from pandemic threats. By using a host cell target as point of intervention, ATRIVA can simultaneously tackle multiple viruses using one target that these viruses require for replication and disease evolution. Through our dual-effect approach, we limit viral proliferation, and cope with the derailed immune system in parallel; at the same time, we avoid resistance formation. This new and exciting anti-viral solution drives us and our work at ATRIVA Therapeutics with the vision to help mankind live a life free from pandemic threats.